Does airway colonization cause systemic inflammation in bronchiectasis?
نویسندگان
چکیده
منابع مشابه
Does airway colonization cause systemic inflammation in bronchiectasis?
Recent evidence suggests the presence of accompanying systemic inflammation in chronic inflammatory airway diseases such as chronic obstructive pulmonary disease and asthma; however little is known regarding the presence of systemic inflammation in bronchiectasis. Although bronchiectasis was initially considered a stationary process, chronic bacterial colonization causes airway inflammation and...
متن کاملThe heterogeneity of systemic inflammation in bronchiectasis.
BACKGROUND Systemic inflammation in bronchiectasis is poorly studied in relation to aetiology and severity. We hypothesized that molecular patterns of inflammation may define particular aetiology and severity groups in bronchiectasis. METHOD We assayed blood concentrations of 31 proteins from 90 bronchiectasis patients (derivation cohort) and conducted PCA to examine relationships between the...
متن کاملSystemic markers of inflammation in stable bronchiectasis.
Patients with bronchiectasis have an active local and systemic inflammatory response during infective exacerbations. Systemic markers of inflammation were investigated during a stable phase of their illness, because continued inflammation could affect their general health and be involved in disease progression. The relationship between levels of various systemic markers of inflammation and exte...
متن کاملAuthor response—vitamin D deficiency and systemic inflammation in bronchiectasis.
Dr Charles Shee raises a further possible explanation for our finding of an association between vitamin D status and disease severity in bronchiectasis, that low vitamin D status represents a negative acute phase response to acute inflammation. Our study was cross-sectional and was unable to establish whether vitamin D deficiency is a cause or consequence of bronchiectasis. Possible explanation...
متن کاملAirway and systemic inflammation in obese children with asthma.
Obese asthma presents via altered airway and systemic inflammation in adults. This has not been comprehensively described in children. The aim of the present study was to compare airway and systemic inflammation in obese and nonobese asthmatic children and controls. In a cross-sectional study, children aged 8-17 years were assigned to one of four groups: obese asthma (OA, n=74); nonobese asthma...
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ژورنال
عنوان ژورنال: Tuberkuloz ve Toraks
سال: 2011
ISSN: 0494-1373
DOI: 10.5578/tt.2934